Alternative splicing (AS) in plants plays a key role in regulating the expression of numerous transcripts from a single gene in a regulatory pathway.Variable concentrations of growth regulatory hormones and external stimuli trigger alternative splicing to Jewelry switch among different growth stages and adapt to environmental stresses.In the AS phe
Abstract Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity.Dune (NCT03095274) is a non-randomized controlled multicohort phase II clinical trial evaluating durvalumab plus tremelimumab activity COCONUT and safety in advanced NENs.This study i
The relentless growth of wireless networks coupled with the burgeoning demand for dynamic resource allocation has spurred research into innovative solutions.This paper presents an evaluation of Cloud-based Dynamic Network Scaling and Slicing (CDNSS) Nits Treatment as a promising approach to meet the evolving demands of wireless networks.By leveragi
Although electron cryo-microscopy (cryo-EM) single-particle analysis has become an important tool for Universal Laptop Charger Power Adaptor structural biology of large and flexible macro-molecular assemblies, the technique has not yet reached its full potential.Besides fundamental limits imposed by radiation damage, poor detectors and beam-induced